Thomas-Crellen-Garscube

Assistant Professor (Research)

CRELLEN, Thomas

Thomas Crellen is an Assistant Professor at the National University of Singapore, Saw Swee Hock School of Public Health. As an infectious disease epidemiologist his research focuses on the transmission, evolution, and control of pathogens with a particular focus on neglected tropical diseases. His past work has made significant contributions to understanding the epidemiology of parasitic diseases, including schistosomiasis and foodborne trematodes, using a combination of field-data collection, statistical modelling, and parasite genomics. At SSHSPH his research aims to understand the dynamics of pathogens in Southeast Asia within the context of changing landscapes, demographics, and urbanization while developing context-relevant interventions for disease control.

Affiliation

  • NUS Saw Swee Hock School of Public Health (Primary)
  • University of Glasgow (Adjunct)

Research Areas

  • Infectious disease dynamics
  • Neglected tropical diseases
  • Pathogen population genomics
  • Inference from diagnostic data

Academic/Professional Qualifications

  • PhD Infectious Disease Epidemiology, Imperial College London (2013 – 2017)
  • MSc Medical Parasitology, London School of Hygiene and Tropical Medicine (2012 – 2013)
  • BA Biological Anthropology, University of Cambridge (2008 – 2011)

Awards/Honours

Career History

  • Wellcome Trust Fellow, University of Oxford and University of Glasgow (2019 – 2024)
  • Computational Biologist, Mahidol-Oxford Research Unit, Thailand (2017 – 2019)
  • Visiting Scientist, Wellcome Sanger Institute (2014 – 2017; 2021 – 2025)
  • Field Epidemiologist, MSF, Central African Republic (2017)

Selected Publications

  • Wangwiwatsin, A., Kulwong, S., Phuyao, C., Titapun, A., Loilome, W., Klanrit, P., Namwat, N., Sithithaworn, P., Doyle, S.R., Berriman, M. and Crellen, T. 2025. The genome sequence of the liver fluke Opisthorchis viverrini (Poirier, 1886) Stiles & Hassall, 1896. Wellcome Open Research, 10
  • Crellen, T., Haswell, M., Sithithaworn, P., Sayasone, S., Odermatt, P., Lamberton, P.H., Spencer, S.E. and Hollingsworth, T.D. 2023. Diagnosis of helminths depends on worm fecundity and the distribution of parasites within hosts. Proc. Roy. Soc. B, 290(1991)
  • Crellen, T., Sithithaworn, P., Pitaksakulrat, O., Khuntikeo, N., Medley, G.F. and Hollingsworth, T.D. 2021. Towards Evidence-based Control of Opisthorchis viverrini. Trends in Parasitology, 37(5)
  • Crellen, T., Pi, L., Davis, E.L., Pollington, T.M., Lucas, T.C., Ayabina, D., Borlase, A., Toor, J., Prem, K., Medley, G.F., Klepac, P. and Hollingsworth, T.D. 2021. Dynamics of SARS-CoV-2 with Waning Immunity in the UK Population. Philos. Trans. R. Soc. B, 376(1829)
  • Crellen, T., Turner, P., Pol, S., Baker, S., Nguyen, T.N.T., Stoesser, N., Day, N.P., Turner, C. and Cooper, B.S. 2019. Transmission dynamics and control of multidrug-resistant Klebsiella pneumoniae in neonates in a developing country. eLife, 8
  • Crellen, T., Walker, M., Lamberton, P.H., Kabatereine, N.B., Tukahebwa, E.M., Cotton, J.A. and Webster, J.P. 2016. Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration. Clinical Infectious Diseases 63(9)

View the full list of publications here

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