Email yeeleong.teoh@cris.sg

Assoc Prof Teoh is a Public Health Physician with extensive expertise in the area of clinical research and infectious disease epidemiology. He obtained his MBBS in 1994 and MMed (Public Health Medicine) in 2003 from National University of Singapore.

He was previously CEO of Singapore Clinical Research Institute from 2013 to 2020 before moving to the current role of Chief Scientific Advisor for Consortium for Clinical Research and Innovation Singapore (CRIS). He also served concurrently as Director, Solutions Technology Evaluation and Piloting, MOH Office of Healthcare Transformation, Senior Consultant, Public Health Group, Ministry of Health.

Prior to coming back to the public sector in 2013, he was Vice-President and General Manager for Emergent Biosolutions Asia Pacific. In that role, he was involved in the development of various vaccines and immunotherapeutic for this Biotech organization. He was also Director, Clinical Research and Medical Affairs for GlaxoSmithKline Singapore, Malaysia and Brunei from 2000 to 2005 where he conducted one of the largest Phase 3 clinical trials in Singapore involving more than 6,000 subjects for a Rotavirus vaccine. In GlaxoSmithKline, he was also managing several clinical trials involving HPV, childhood pneumococcal, flu, pandemic flu and MMRV combination vaccines.

Assoc Prof Teoh’s previous other senior appointments included being Assistant Commissioner of Public Health (Ministry of the Environment), Physician and Head, Jurong Polyclinic (National Healthcare Group Polyclinics) and Infectious Disease Epidemiologist (Communicable Disease Centre, Tan Tock Seng Hospital, Singapore).

• NUS Saw Swee Hock School of Public Health (Adjunct)
• Chief Scientific Advisor, Consortium of Clinical Research and Innovation, Singapore (Primary)
• Senior Consultant, Public Health Group, Ministry of Health
• Director, Solutions & Technology Evaluation and Piloting, Ministry of Health Office of Healthcare Transformation

• Infectious disease prevention and control
• Chronic disease and cancer epidemiology
• Healthcare services

• Infectious disease prevention and control
• Chronic disease epidemiology
• Research methodology

• MBBS, Singapore 1994
• MMed (Public Health Medicine), NUS, 2003
• Fellow of Academy of Medicine Singapore, 2007

• Infectious Disease Prevention and Control
• Clinical Research
• Chronic disease and cancer epidemiology

• Teoh YL, Goh KT, Neo KS, Yeo M. A nationwide outbreak of coconut-associated paratyphoid A fever in Singapore. Ann Acad Med Singapore, 26(5):544-8. 1997.
• Teoh YL, Soh E, Heng J, BH Heng, Cheah J. A KAP survey of evidence-based medicine and clinical practice guidelines among primary care doctors in Singapore. Ann Acad Med Singapore, Sep 2004
• Shir Lynn Lim, Mihir Gandhi, Kai Lee Woo, Horng Ruey Chua, Yoke Ching Lim, David K.L. Sim, Sheldon S.G. Lee, Yee Leong Teoh, Arthur Mark Richards, Carolyn S.P. Lam Nitrates in combination with hydralazine in cardiorenal syndrome: a randomized controlled proof‐of‐concept study. ESC Heart Failure (2020)
• Sarah Ee Fang Yong, Danielle Elizabeth Anderson, Wycliffe E Wei, Junxiong Pang, Wan Ni Chia, Chee Wah Tan, Yee Leong Teoh, Priyanka Rajendram, Matthias Paul Han Sim Toh, Cuiqin Poh, Valerie T J Koh, Joshua Lum, Nur-Afidah Md Suhaimi, Po Ying Chia, Mark I-Cheng Chen, Shawn Vasoo, Benjamin Ong, Yee Sin Leo, Linfa Wang, Vernon J M Lee. Connecting clusters of COVID-19: an epidemiological and serological investigation. www.thelancet.com/infection Vol 20 July 2020
• Lau WY, Teoh YL, Win KM, Lee RC, de Villa VH, Kim YH, Liang PC, Santos-Ocampo RS, Lo RH, Lim KB, Tai DW, Ng DC, Irani FG, Gogna A, Chow PK. Current role of selective internal radiation with yttrium-90 in liver tumors. Future Oncol. 2016 Mar 23
• Lim BK, Ng KY, Omar J, Omar SZ, Gunapalaiah B, Teoh YL, Bock HL, Bi D. Immunogenicity and Safety of the AS04-adjuvanted Human Papillomavirus-16/18 Cervical Cancer Vaccine in Malaysian Women Aged 18-35 years: A Randomized Controlled Trial. Med J Malaysia. 2014 Feb; 69(1):2-8.
• Phua KB, Tee N, Tan N, Ramakrishnan G, Teoh YL, Bock H, Liu YF. A Hospital-Based Surveillance of Rotavirus Gastroenteritis in Children <5 Years of Age in Singapore. Pediatr Infect Dis J. 2013 Aug 16
• Phua KB, Lim FS, Lau YL, Nelson EA, Huang LM, Quak SH, Lee BW, van Doorn LJ, Teoh YL, Tang H, Suryakiran PV, Smolenov IV, Bock HL, Han HH. Rotavirus vaccine RIX4414 efficacy sustained during the third year of life: a randomized clinical trial in an Asian population. Vaccine. 2012 Jun 22;30(30):4552-7.
• Lee VJ, Tay SK, Teoh YL, Tok MY. Cost effectiveness of different human papillomavirus vaccines in Singapore. BMC Public Health 2011 Mar 31, 11 (1): 203
• Lim FS, Phua KB, Lee BW, Quak SH, Teoh YL, Ramakrishnan G, Han HH, Van Der Meeren O, Jacquets JM, Bock HL.Safety and reactogenicity of DTPa-HBV-IPV/Hib and DTPa-IPV/Hib vaccines in a post marketing surveillance setting. Southeast Asian J Trop Med Public Health. 2011 Jan;42(1):138-47.
• Tan E K, Lim L H, Teoh Y L, Ong G, Bock H L. Influenza and seasonal influenza vaccination among diabetics in Singapore: knowledge, attitudes and practices. Singapore Med J 2010; 51(8) : 623-630
• Fong Seng Lim, Kah Kee Tan, Poh Chong Chan, Chia Yin Chong, Mia Tuang Koh, Yee Leong Teoh, Aurélie Fanic, Ilse Dieussaert, Kristien Swinnen, Dorota Borys. Immunogenicity of A 3-Dose Primary Series Of The Pneumococcal Non-Typeable Haemophilus Influenzae Protein-D Conjugate Vaccine (Phid-Cv) In Healthy Malaysian And Singaporean Infants. Malaysian Journal of Paediatrics and Child Health 2010 (Dec); Vol. 16; Supplementary 2
• Tan N, Teoh YL, Phua KB, Quak SH, Lee BW, Teo HJ, Jacobsen A, Boudville IC, Ng T, Verstraeten T, Bock HL. An update of paediatric intussusception incidence in Singapore: 1997-2007, 11 years of intussusception surveillance. Ann Acad Med Singapore. 2009 Aug;38(8):690-2.
• Fong Seng LIM, Kong Boo PHUA, Bee Wah LEE, Seng Hock QUAK, Yee Leong TEOH, Gunasekaran RAMAKRISHNAN, Htay-Htay HAN, Olivier VAN DER MEEREN, Jeanne-Marie JACQUET, Hans L BOCK. Safety and reactogenicity of DTPa-HBV-IPV/Hib and DTPa-IPV/Hib vaccines in post-marketing surveillance setting. Southeast Asian Journal of Tropical Medicine and Public Health; Volume 42 No.1, January 2011.
• Chu DW, Hwang SJ, Lim FS, Oh HM, Thongcharoen P, Yang PC, Bock HL, Dramé M, Gillard P, Hutagalung Y, Tang H, Teoh YL, Ballou RW. Immunogenicity and tolerability of an AS03(A)-adjuvanted prepandemic influenza vaccine: A phase III study in a large population of Asian adults. Vaccine. 2009 Aug 12.
• Phua KB, Lim FS, Lau YL, Nelson EA, Huang LM, Quak SH, Lee BW, Teoh YL, Tang H, Boudville I, Oostvogels LC, Suryakiran PV, Smolenov IV, Han HH, Bock HL. Safety and efficacy of human rotavirus vaccine during the first 2 years of life in Asian infants: Randomised, double-blind, controlled study. Vaccine. 2009 Aug 11
• CL Giak, HSS Amar Singh, R Nallusamy, Teoh Yee Leong, Timothy L Ng, Hans L Bock. Epidemiology of intussusception in Malaysia. A three year review. The Southeast Asian Journal of Tropical Medicine and Public Health, 39 (5), Sep 2009.
• KB Phua, SH Quak, FS Lim, P Goh, Teoh YL, S Datta, HH Han, HL Bock. Immunogenicity, Reactogenicity and Safety of a Diptheria-Tetanus-Acellular Pertussis-Inactivated Polio and Haemophilus Influenzae Type b combination vaccine in a placebo-controlled Rotavirus Vaccine Study. Ann Acad Med Singapore 2008, 37 (7) : 546-553
• Wong SL, Soosai P, Teoh YL, Han HH, Lefevre I, Bock H. Four is better than nine. A combined diphtheria-tetanus-pertussis-hepatitis B-Haemophilus influenza type b vaccine for routine immunization in Malaysia. Southeast Asian J Trop Med Public Health, Vol 39, No. 3, May 2008
• Chai LY, Lim PL, Lee CC, Hsu LY, Teoh YL, Lye DC, Krishnan P, Leo YS. Cluster of Staphylococcus aureus and Dengue Co-infection in Singapore.. Ann Acad Med Singapore. 2007 Oct;36(10):847
• Fock KM, Khor CJL, Goh KT, Teoh YL, Seow A, Chia KS et al. Seroprevalence of Helicobacter pylori infection and the incidence of gastric cancer in a multi-ethnic population. Gut 1997; 41 (Suppl. 1): A50.
• Goh KT, Teoh YL, Ng HC, Heng BH, Khor CJL, Fock KM, et al. Seroprevalence of Helicobacter pylori infection in Singapore. Helicobacter 1996; 1(4):A12.
• A Berrhouma, KS Chia, AJC Delchier, JE Dominguezmunoz, KM Fock, KT Goh, B Ho, S Kamiya, CJL Khor, N Kurihara, P Malfertheiner, G Manes, HC Ng, T Osaki, A Seow, E Sevin, J Tankovic, YL Teoh. Role of heat-shock-protein-60 homolog of Helicobacter pylori for human chronic gastric inflammation following Helicobacter pylori infection. Gut 1997. 41, C. A 24-a24.
• Goh V, Teoh. Picking the Right Hospital, Right Doctor in Singapore. A book on healthcare services in Singapore published by Rankbooks in Sep 2006.