Tel (65) 6436 8574
Email iain.tan.b.h@singhealth.com.sg

I am a senior consultant medical oncologist and Director of research at the Division of Medical Oncology at National Cancer Centre Singapore. I am also the platform lead for databases and biobanks at the Singapore Translational Cancer Consortium (STCC) under CRIS,MOH. I take the lead on population health research & innovation at National Cancer Centre Singapore.

We are creating the national cancer dataset based as the cancer data commons within Singapore Translational Cancer Consortium (STCC) in collaboration with the three public healthcare sectors and IHIS. CDC contains the anonymized/de-identified cancer health information of all cancer patients receiving care at the 3 public healthcare clusters for the last 12 years, linked together through iHIS BRAIN. Through this, we will be performing research across the domains of pre-cancer screening survivorship of consideration and effectiveness of current cancer care and end of life care, throughout the continuum of the patient cancer journey. We are particularly interested in the health economics of precision oncology including the use of precision diagnostics to stratify patients into current therapeutics. I have also been fortunate to be involved in the management of COVID as a member of the joint task force, helping with the management of the COVID epidemic in the healthcare dormitories. Cancer research and population health can make an impact in Singapore. Do reach out to me to exchange ideas for possible collaborations.

• NUS Saw Swee Hock School of Public Health (Joint Associate Professor)
• National Cancer Centre Singapore, Senior Consultant Medical Oncologist and Director of Research, Division of Medical Oncology
• Genome Institute of Singapore, Senior Clinician Scientist
• Duke-NUS, Associate Professor, Cancer and Stem Cell Biology Programme

• Cancer Genomics
• Colorectal Cancer
• Non-invasive Diagnostics
• Immunology
• Population health

• Doctor of Philosophy, National University of Singapore, 2014
• Member, Royal College of Physicians UK, 2007
• Bachelor of Medicine, Bachelor of Surgery, National University of Singapore, 2002

• National Youth Award

• Senior Consultant Medical Oncologist, Division of Medical Oncology,

• Director of Research, Division of Medical Oncology
• Platform Lead for population health and impact (Platform 5) and cancer data banks and bio banking (Platform 2) Singapore Translational Cancer Consortium (STCC), Consortium for Clinical Research and Innovation Singapore. (CRIS)

• Ignasius Joanito, Pratyaksha Wirapati, Nancy Zhao, Zahid Nawaz, Grace Yeo, Fiona Lee, Christine LP Eng, Dominique Camat Macalinao, Merve Kahraman, Harini Srinivasan, Vairavan Lakshmanan, Sara Verbandt, Petros Tsantoulis, Nicole Gunn, Prasanna Nori Venkatesh, Zhong Wee Poh, Rahul Nahar, Hsueh Ling Janice Oh , Loo Jia Min, Chia Shumei, Cheow Lih Feng, Elsie Cheruba, Michael Thomas Wong, Lindsay Kua, Clarinda Chua, Andy Nguyen, Justin Golovan, Anna Gan, Wan-Jun Lim, Yu Amanda Guo, Choon Kong Yap, Brenda Tay, Yourae Hong, Dawn Qingqing Chong, Aik-Yong Chok, Woong-Yang Park, Shuting Han, Meihuan Chang, Isaac Seow-En, Cherylin Fu, Ronnie Mathew, Ee-Lin Toh, Lewis Z Hong, Anders Jacobsen Skanderup, Ramanuj DasGupta, Chin-Ann Johnny Ong-, Kiat Hon Lim, Emile KW Tan, Si-Lin Koo, Wei Qiang Leow, Sabine Tejpar*, Shyam Prabhakar*, Iain Beehuat Tan*. *Co-corresponding author. Single-cell and bulk transcriptome sequencing identifies two epithelial tumour cell states and refines the consensus molecular classification of colorectal cancer Nat Genet. 2022 Jul;54(7):963-975. doi: 10.1038/s41588-022-01100-4. Epub 2022 Jun 30.
• Tan IB, Tan C, Hsu LY, Dan YY, Aw A, Cook AR, Lee VJ. Prevalence and Outcomes of SARS-CoV-2 Infection Among Migrant Workers in Singapore. JAMA. 2021 Feb 9;325(6):584-585. doi: 10.1001/jama.2020.24071.
• Simoni Yannick; Becht Etienne; Fehlings Michael; Loh Chiew Yee; Koo Si-Lin; Teng Karen Wei Weng; Yeong Joe Poh Sheng; Nahar Rahul; Zhang Tong; Kared Hassen; Duan Kaibo; Ang Nicholas; Poidinger Michael; Lee Yin Yeng; Larbi Anis; Khng Alexis J; Tan Emile; Fu Cherylin; Mathew Ronnie; Teo Melissa; Lim Wan Teck; Toh Chee Keong; Ong Boon-Hean; Koh Tina; Hillmer Axel M; Takano Angela; Lim Tony Kiat Hon; Tan Eng Huat; Zhai Weiwei; Tan Daniel S W; Tan Iain Beehuat; Newell Evan W.Bystander CD8 T cells are abundant and phenotypically distinct in human tumour infiltrates.Nature 2018; 557(7706):575-579 (Article; Published in Print)
• Suzuki Yuka; Ng Sarah Boonhsi; Chua Clarinda; Leow Wei Qiang; Chng Jermain; Liu Shi Yang; Ramnarayanan Kalpana; Gan Anna; Ho Dan Liang; Ten Rachel; Su Yan; Lezhava Alexandar; Lai Jiunn Herng; Koh Dennis; Lim Kiat Hon; Tan Patrick; Rozen Steven G; Tan Iain Beehuat
  Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.
  Molecular oncology 2017; 11(2):124-139 (Article; Published in Print)
• Ng SB, Chua C, Ng M, Gan A, Poon PS, Teo M, Fu C, Leow WQ, Lim KH, Chung A, Koo SL, Choo SP, Ho D, Rozen S, Tan P, Wong M, Burkholder WF, Tan IB.
  Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery.Sci Rep. 2017; 7:N.A.-N.A. (Article; Published in Print)
• Li Huipeng; Courtois Elise T; Sengupta Debarka; Tan Yuliana; Chen Kok Hao; Goh Jolene Jie Lin; Kong Say Li; Chua Clarinda; Hon Lim Kiat; Tan Wah Siew; Wong Mark; Choi Paul Jongjoon; Wee Lawrence J K; Hillmer Axel M; Tan Iain Beehuat*; Robson Paul*; Prabhakar Shyam* *Co-corresponding author
  Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors.
  Nature genetics 2017; 49(5):708-718 (Article; Published in Print)
• Fukawa Tomoya; Yan-Jiang Benjamin Chua; Min-Wen Jason Chua; Jun-Hao Elwin Tan; Huang Dan; Qian Chao-Nan; Ong Pauline; Li Zhimei; Chen Shuwen; Mak Shi Ya; Lim Wan Jun; Kanayama Hiro-Omi; Mohan Rosmin Elsa; Wang Ruiqi Rachel; Lai Jiunn Herng; Chua Clarinda; Ong Hock Soo; Tan Ker-Kan; Ho Ying Swan; Tan Iain Beehuat*; Teh Bin Tean*; Shyh-Chang Ng* *Co-corresponding author
  Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia.
  Nature medicine 2016; 22(6):666-71 (Article; Published in Print)
• Tan IB, Malik S, Ramnarayanan K, McPherson JR, Ho DL, Suzuki Y, Ng SB, Yan S, Lim KH, Koh D, Hoe CM, Chan CY, Ten R, Goh BK, Chung AY, Tan J, Chan CX, Tay ST, Alexander L, Nagarajan N, Hillmer AM, Tang CL, Chua C, Teh BT, Rozen S, Tan P. High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.
  Genome Biology 2015; 16(1):N.A.-N.A. (Article; Published in Print)
• Tan Iain Beehuat; Ivanova Tatiana; Lim Kiat Hon; Ong Chee Wee; Deng Niantao; Lee Julian; Tan Sze Huey; Wu Jeanie; Lee Ming Hui; Ooi Chia Huey; Rha Sun Young; Wong Wai Keong; Boussioutas Alex; Yeoh Khay Guan; So Jimmy; Yong Wei Peng; Tsuburaya Akira; Grabsch Heike; Toh Han Chong; Rozen Steven; Cheong Jae Ho; Noh Sung Hoon; Wan Wei Kiat; Ajani Jaffer A; Lee Ju-Seog; Tellez Manuel Salto; Tan Patrick.Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy.
  Gastroenterology 2011; 141(2):476-85, 485.e1 (Article; Published in Print)
• Tan Iain Beehuat; Cutcutache Ioana; Zang Zhi Jiang; Iqbal Jabed; Yap Seow Fong; Hwang William; Lim Wan-Teck; Teh Bin Tean; Rozen Steve; Tan Eng-Huat; Tan Patrick.Fanconi’s anemia in adulthood: chemoradiation-induced bone marrow failure and a novel FANCA mutation identified by targeted deep sequencing.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011; 29(20):e591-4 (Article; E-Published Only (Never in Print)/E-collection)