Tel (65) 6516 4973
Fax (65) 6779 1489
Email ephtbc@nus.edu.sg

• NUS Saw Swee Hock School of Public Health (Primary)
• NUS Yong Loo Lin School of Medicine (Joint)

• Design, conduct and analysis of clinical trials
• Non-compliance in randomised clinical trials
• Meta-analysis with trial sequential analysis of randomised clinical trials
• Competing risks and strategies for handling non-proportional hazards

• Basic and Advanced Biostatistics
• Design, conduct and analysis of clinical trials

• Bachelor of Arts (1985); National University of Singapore
• Graduate Diploma in Statistics (1991); The Institute of Statisticians, United Kingdom
• MSc Medical Statistics (with distinction) (1995); London Sch Hygiene & Tropical Medicine, University of London
• PhD Medical Statistics (2005); London Sch Hygiene & Tropical Medicine, University of London

• Elected Chartered Statistician of the Royal Statistical Society (UK) since 1997
• Saw Swee Hock School of Public Health Teaching Excellence Award AY2015/16
• Saw Swee Hock School of Public Health Teaching Excellence Award AY2021/22

• Lecturer in Business Statistics (1989 – 1994); Ngee Ann Polytechnic, Singapore
• Biostatistician (1995 – 1997); National University Medical Institute, National University of Singapore
• Senior Medical Statistician (1997 – 2003); Clinical Trials & Epidemiology Research Unit, Singapore
• Research Fellow (2003 – 2007); Centre for Molecular Epidemiology; Dept of Community, Occupational & Family Medicine, National University of Singapore
• Associate Professor (2007 – Present); Saw Swee Hock School of Public Health, National University of Singapore
• Joint Associate Professor (2011 – Present); Yong Loo Lin School of Medicine, National University of Singapore
• Affiliate (2014 – Present), National University Cancer Institute, Singapore, National University Health System. Core
  Director of the Biostatistics Division for the NCIS Centre grant.

• Expert Biostatistician on the Review Panel for the 2022 Clinical Trials Activity Grant Opportunity of the Australian
  Government’s (NHMRC) Medical Research Future Fund, Oct – Nov 2023.
• Member of National University Health System (NUHS) Seed Grant Review Panel, 2021 – Present.
• Member of Faculty Research Committee, National University of Singapore, 2018 – 2022.
• Member of National Medical Research Council, Singapore, Scientific Review Panel, 2007 – 2017.
• Member of Singapore Civil Defence Force Department Research Ethics Review Committee, 2021 – Present.
• Member of the Data and Safety Monitoring Board for the INVEST trial, National Centre for Infectious Diseases
  (NCID), 2022 – Present.
• Statistical Consultant to SingHealth Regional Health System on the design and analysis of clinical trials, 2022 –
  Present.
• Statistical Consultant for Agency for Integrated Care (AIC) Pte Ltd, Research and Development Office, 2019 – Present.
• Statistical Consultant for the Surveillance and Pharmacogenomics Initiative for Adverse Drug Reactions (SAPhIRE)
  project, Health Sciences Authority, Vigilance and Compliance Branch in, 2015 – 2018.
• Member of Programme Review Panel for the MSc/Postgraduate Diploma in Epidemiology and Biostatistics
  Programme, JC School of Public Health and Primary Care, The Chinese University of Hong Kong, June 2019.
• Invited faculty member for workshops conducted for Boehringer Ingelheim Singapore Pte. Ltd (2016), Boehringer
  Ingelheim Metabolic Group, South East Asia and South Korea (2019) and National Pharmaceutical Regulatory
  Agency, Ministry of Health Malaysia on behalf of Boehringer Ingelheim (Malaysia) Sdn. Bhd (2018, 2019)
• Invited faculty member of the Australia & Asia Pacific Clinical Oncology Research Development (ACORD) online
  Protocol Development Workshop (2020 − 2022) organised by the NHMRC Clinical Trials Unit, University of Sydney.
• Invited faculty member of the SSO-ACORD Concept Development Workshop (2019) jointly organised by the
  NHMRC Clinical Trials Unit, University of Sydney and the Singapore Society of Oncology.
• Associate Editor, Pharmaceutical Statistics, 2017 – Present

• Tai BC and Machin D (2014). Regression Methods for Medical Research. Wiley-Blackwell.
• Tai BC , Chen ZJ and Machin D (2018). Estimating sample size in the presence of competing risks – Cause-specific
  hazard or cumulative incidence approach? Statistical Methods for Medical Research, 27: 114 – 125.
• Yang HK, Ji JF, Han SU, Terashima M, Li GX, Kim HH, Law S, Shabbir A, Song KY, Hyung WJ, Kosai NR, Kono K,
  Ito S, Yabusaki H, Kinoshita T, Lau PC, Kim YW, Rao J, Ng E, Yoshida K, Park DJ, Tai BC, So JBY (2021). Extensive
  peritoneal lavage after curative gastrectomy for gastric cancer (EXPEL): An international multi-center randomized
  controlled Phase III trial. Lancet Gastroenterology and Hepatology, 6: 120 -127.
• Syn NL, Cummings DE, Wang LZ, Lin DJ, Zhao JJ, Loh M, Koh ZJ, Chew CA, Loo YE, Tai BC, et al (2021).
  Association of metabolic-bariatric surgery with long-term survival in obese adults with and without diabetes: a patient
  level meta-analysis of 174,772 participants with 1·2 million patient-years of follow-up. Lancet, 397: 1830–41.
• Machin D, Fayers PM and Tai BC (2021). Randomized Clinical Trials: Design, Practice and Reporting. 2nd Ed. Wiley
  Blackwell.
• Ling RR, Kollengode R, Tan FL, Tai BC , Somani J, Fisher D, MacLaren G (2022). Vaccine-induced myopericarditis:
  a systematic review and meta-analysis. Lancet Respiratory Medicine, 10: 679 – 688.
• Tai BC and Machin D (2024). Clinical Trials. International Encyclopedia of Public Health. 3rd Ed. Elsevier.

• 减重代谢手术料助肥胖与糖尿病患延长预期寿命达六年, Shin Min Daily News, 12 May 2021
• Surgery may lower mortality rate for obese adults: Singapore study, BioSpectrum Asia Edition, 14 May 2021
• Related: Weight-loss surgery helps obese patients live longer: Study, CNA Singapore Tonight, 12 May 2021

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