Tel (65) 6306 5916
Email gmscqd@nus.edu.sg

I am a Senior Consultant Medical Oncologist at the Division of Medical Oncology, National Cancer Centre Singapore (NCCS) and specialize in gastrointestinal cancers. I am the lead for cancer screening at NCCS and the co-lead for Impact and Population Health (Platform 5) of the Singapore Translational Cancer Consortium (STCC) under Consortium for Clinical Research and Innovation Singapore (CRIS), Ministry of health (MOH). My research interests include cancer epidemiology, leveraging on epidemiological and clinical datasets to inform population health approaches/policy and novel cancer screening methodologies. I work on initiatives with the aim of improving cancer screening rates, cancer detection and public health outcomes.

• NUS Saw Swee Hock School of Public Health (Joint Assistant Professor)
• National Cancer Centre Singapore Senior Consultant Medical Oncologist
• Duke-NUS Medical School Assistant Professor
• Yong Loo Lin School of Medicine Clinical Lecturer

• Cancer Epidemiology
• Colorectal Cancer
• Population Health

• Oncology

• B.B.S National University of Singapore, Singapore 2006
• MRCP Royal College of Physicians, Glasgow (UK) 2010
• MPH Harvard T.H. Chan School of Public Health 2016

• Singhealth Health Manpower Development Plan (HMDP) Fellowship award in 2013
• National Medical Research Council (NMRC) Clinician Scientist Individual Research Grant New Investigator Grant (CS-IRG NIG) 2015
• NMRC Research Training Fellowship in 2015
• NMRC Transition Award 2018

• Assistant Professor Duke NUS Medical School 2019 – present
• Senior Consultant NCCS 2020 – present

• Co-lead of Impact and Population Health (Platform 5) of Singapore Translational Cancer Consortium (STCC), Consortium for Clinical Research and Innovation Singapore (CRIS)
• Lead of Cancer Screening, Office of Population Health, National Cancer Centre Singapore
• Vice President, Singapore Society of Oncology

• Mehta RS, Chong DQ, Song M, Meyerhardt JA, Ng K, Nishihara R, Qian Z, Morikawa T, Wu K, Giovannucci EL, Fuchs CS, Ogino S, Chan AT. Association Between Plasma Levels of Macrophage Inhibitory Cytokine-1 Before Diagnosis of Colorectal Cancer and Mortality. Gastroenterology. 2015 Sep;149(3):614-22
• Chong DQ, Mehta RS, Song M, Kedrin D, Meyerhardt JA, Ng K, Wu K, Fuchs CS, Giovannucci EL, Ogino S, Chan AT. Prediagnostic Plasma Adiponectin and Survival among Patients with Colorectal Cancer. Cancer Prev Res (Phila). 2015 Dec;8(12):1138-45.
• Simon TG, King LY, Chong DQ, Nguyen LH, Ma Y, VoPham T, Giovannucci EL, Fuchs CS, Meyerhardt JA, Corey KE, Khalili H, Chung RT, Zhang X, Chan AT. Diabetes, metabolic comorbidities, and risk of hepatocellular carcinoma: Results from two prospective cohort studies. Hepatology. 2018 May;67(5):1797-1806
• Chong DQ, Banbury BL, Phipps AI, Hua X, Kocarnik J, Peters U, Berndt SI, Huang WY, Potter JD, Slattery ML, White E, Campbell PT, Harrison T, Newcomb PA, Chan AT. Association of family history and survival in patients with colorectal cancer: a pooled analysis of eight epidemiologic studies. Cancer Med. 2018 Mar 26.
• Ma Y, Yang W, Simon TG, Smith-Warner SA, Fung TT, Sui J, Chong D, VoPham T, Meyerhardt JA, Wen D, Giovannucci EL, Chan AT, Zhang X. Dietary patterns and risk of hepatocellular carcinoma among US men and women. Hepatology. 2018 Dec 1. doi: 10.1002/hep.30362
• Simon TG, Ma Y, Ludvigsson JF, Chong DQ, Giovannucci EL, Fuchs CS, Meyerhardt JA, Corey KE, Chung RT, Zhang X, Chan AT. Association Between Aspirin Use and Risk of Hepatocellular Carcinoma. JAMA Oncol. 2018 Dec 1;4(12):1683-1690. doi: 10.1001/jamaoncol.2018.4154. Erratum in: JAMA Oncol. 2019 Apr 1;5(4):579.
• Yang W, Ma Y, Liu Y, Smith-Warner SA, Simon TG, Chong DQ, Qi Q, Meyerhardt JA, Giovannucci EL, Chan AT, Zhang X. Association of Intake of Whole Grains and Dietary Fiber With Risk of Hepatocellular Carcinoma in US Adults. JAMA Oncol. 2019 Jun 1;5(6):879-886. doi: 10.1001/jamaoncol.2018.7159
• Petrick JL, Florio AA, Zhang X, Zeleniuch-Jacquotte A, Wactawski-Wende J, Van Den Eeden SK, Stanczyk FZ, Simon TG, Sinha R, Sesso HD, Schairer C, Rosenberg L, Rohan TE, Purdue MP, Palmer JR, Linet MS, Liao LM, Lee IM, Koshiol J, Kitahara CM, Kirsh VA, Hofmann JN, Guillemette C, Graubard BI, Giovannucci E, Gaziano JM, Gapster SM, Freedman ND, Engel LS, Chong DQ, Chen Y, Chan AT, Caron P, Buring JE, Bradwin G, Beane Freeman LE, Campbell PT, McGlynn KA. Associations Between Prediagnostic Concentrations of Circulating Sex Steroid Hormones and Liver Cancer Among Postmenopausal Women. Hepatology. 2020 Aug;72(2):535-547. doi: 10.1002/hep.31057
• Simon TG, Kim MN, Luo X, Yang W, Ma Y, Chong DQ, Fuchs CS, Meyerhardt JA, Corey KE, Chung RT, Stampfer M, Zhang X, Giovannucci EL, Chan AT. Physical Activity Compared to Adiposity and Risk of Liver-Related Mortality: Results from Two Prospective, Nationwide Cohorts. J Hepatol. 2020 Jun;72(6):1062-1069. doi: 10.1016/j.jhep.2019.12.022. Epub 2020 Jan 15.
• Zhu G, Guo YA, Ho D, Poon P, Poh ZW, Wong PM, Gan A, Chang MM, Kleftogiannis D, Lau YT, Tay B, Lim WJ, Chua C, Tan TJ, Koo SL, Chong DQ, Yap YS, Tan I, Ng S, Skanderup AJ. Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden. Nat Commun. 2021 Apr 13;12(1):2229
• Joanito I, Wirapati P, Zhao N, Nawaz Z, Yeo G, Lee F, Eng CLP, Macalinao DC, Kahraman M, Srinivasan H, Lakshmanan V, Verbandt S, Tsantoulis P, Gunn N, Venkatesh PN, Poh ZW, Nahar R, Oh HLJ, Loo JM, Chia S, Cheow LF, Cheruba E, Wong MT, Kua L, Chua C, Nguyen A, Golovan J, Gan A, Lim WJ, Guo YA, Yap CK, Tay B, Hong Y, Chong DQ, Chok AY, Park WY, Han S, Chang MH, Seow-En I, Fu C, Mathew R, Toh EL, Hong LZ, Skanderup AJ, DasGupta R, Ong CJ, Lim KH, Tan EKW, Koo SL, Leow WQ, Tejpar S, Prabhakar S, Tan IB. Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer. Nat Genet. 2022 Jul;54(7):963-975. doi: 10.1038/s41588-022-01100-4.
• Chong DQ, Manalo M, Imperial M, Teo P, Yong G, Ng M, Tan IB, Choo SP, Chua C. Safety and efficacy of aflibercept in combination with fluorouracil, leucovorin and irinotecan in the treatment of Asian patients with metastatic colorectal cancer. Asia Pac J Clin Oncol. 2016 Sep;12(3):275-83.
• Shanmugam R, Majee P, Shi W, Ozturk MB, Vaiyapuri TS, Idzham K, Raju A, Shin SH, Fidan K, Low JL, Chua JYH, Kong YC, Qi OY, Tan E, Chok AY, Seow-En I, Wee I, Macalinao DC, Chong DQ, Chang HY, Lee F, Leow WQ, Murata-Hori M, Xiaoqian Z, Shumei C, Tan CSH, Dasgupta R, Tan IB, Tergaonkar V. Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers. Cancer Discov. 2024 Oct 4;14(10):1940-1963
• Zhu G, Rahman CR, Getty V, Odinokov D, Baruah P, Carrié H, Lim AJ, Guo YA, Poh ZW, Sim NL, Abdelmoneim A, Cai Y, Lakshmanan LN, Ho D, Thangaraju S, Poon P, Lau YT, Gan A, Ng S, Koo SL, Chong DQ, Tay B, Tan TJ, Yap YS, Chok AY, Ng MCH, Tan P, Tan D, Wong L, Wong PM, Tan IB, Skanderup AJ. A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths. Nat Biomed Eng. 2025 Mar;9(3):307-319
• Gandhi M, Kanesvaran R, Rashid MFBH, Chong DQ, Chay WY, Tan RL, Norman R, King MT, Luo N. Valuation of the EORTC Quality of Life Utility Core 10 Dimensions (QLU-C10D) in a Multi-ethnic Asian Setting: How Does Having Cancer Matter? Pharmacoeconomics. 2024 Dec;42(12):1413-1425.